Journal of Basic and Applied Research International
 

Journal of Basic and Applied Research International, ISSN No. : 2395-3438 (Print), 2395-3446 (Online), Vol.: 21, Issue.: 3

Short Research Article

VITAMINS C AND E PARTIALLY REVERSE HISTOLOGICAL ALTERATION INDUCED BY ADMINISTRATION OF TETRACYCLINE IN DENTIN OF NEONATE RATS

 

CAREN SERRA BAVARESCO1,2*, ANDRE ROTTA SEBBEN1, MARCELO GARCIA DASSOW1, MYRIAN CAMARA BREW1, PEDRO ANTONIO GONZÁLEZ HERNÁNDEZ1 AND ADAIR LUIZ STEFANELLO BUSATO1

1School of Dentistry, Universidade Luterana do Brasil (ULBRA), Canoas, RS, Brazil.

2Department of Oral Health, Grupo Hospitalar Conceição, Porto Alegre, RS, Brazil.

Abstracts

This study sought to verify the role of antioxidants over the intensity of fluorescence in the dental tissue of rats induced by tetracycline. Wistar rats were divided into 4 experimental groups and tooth slides were microscopically observed by fluorescence. Results demonstrated intense fluorescence in the dentine matrix of the slides of the rats which had received tetracycline and slight fluorescence in those which had received tetracycline and vitamin, suggesting partial reverse of oxidative stress. No alterations of fluorescence were observed in the enamel matrix.

Keywords :

Tetracycline; tooth discoloration; vitamins C and E; oxidative stress.